S. Isaac, Campbell & Company opened its first merchant store in Chatham, Kent in 1838.
A corruption scandal in June 1858 charged the firm with bribery and malfeasance regarding inferior goods supplied to the military.
Major Caleb Huse arrived in Liverpool on the 10th of May 1861 as head purchasing agent for Europe representing the Confederate War Department.
By November 1862 the Confederacy owed $2,000,000 to S. Isaac, Campbell & Company from supplies shipped before the end of that year.
The collapse of cotton securities following General Grant's victory at Vicksburg in July 1863 forced the company into declaring bankruptcy in 1869.