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— CH. 1 · INTRODUCTION —

Bayer

~7 min read · Ch. 1 of 7
7 sections
  • Bayer AG began not as a pharmaceutical giant but as a dyestuffs factory in Barmen, Germany, in 1863. Friedrich Bayer, a dye salesman, and Johann Friedrich Weskott, a master dyer, formed a partnership to sell fuchsine and aniline dyes. Neither man could have imagined that aniline chemistry would eventually lead their small firm toward medicines, insecticides, and one of the most controversial corporate acquisitions in modern history. What happens when a company built on color pigments becomes the maker of aspirin, heroin, and Roundup weedkiller? And what does it mean that the same corporate lineage runs from a Nobel Prize in medicine to the gas chambers of Auschwitz? These are the questions Bayer's story forces us to ask.

  • Acetylsalicylic acid had actually been described by French chemist Charles Frederic Gerhardt back in 1853, before Bayer ever touched it. Bayer scientists worked to refine the compound, and by 1899 the trademarked name Aspirin was registered worldwide. The drug's origins, however, remain disputed. Arthur Eichengrün, a Bayer chemist who was imprisoned at Theresienstadt concentration camp in 1944, claimed he was the first to develop a formulation that eliminated the nausea and gastric pain that plagued earlier versions. He also said he invented the name and first tested the compound himself. Bayer's official account attributed the discovery to Felix Hoffmann, described as an Aryan research assistant motivated by his father's arthritis. Most mainstream historians today credit both Hoffmann and Eichengrün without resolving the dispute cleanly. Whatever the origins, the product's reach became staggering: by 2011, roughly 40,000 tons of aspirin were produced each year, with 10-20 billion tablets consumed in the United States alone. Aspirin's standing is now so established that it sits on the World Health Organization's List of Essential Medicines. Bayer lost the aspirin trademark in the United States, France, and the United Kingdom after its American assets were confiscated during World War I, but the name remains a registered Bayer trademark in more than 80 countries, including Canada, Germany, and Switzerland.

  • Heroin was a Bayer trademark. From 1898 to 1910, Bayer marketed diacetylmorphine as a cough suppressant and over-the-counter treatment for pneumonia and tuberculosis, presenting it as a non-addictive substitute for morphine. Bayer's director of pharmacology wanted a name that avoided anything too complicated, so the company chose heroisch, the German word for heroic. Bayer's scientists did not synthesize heroin first, but the company was the driving force in making it commercially available. In 1903, Bayer licensed the patent for diethylbarbituric acid from chemists Emil Fischer and Joseph von Mering, marketing it as the sleep aid Veronal. Further research at Bayer led to phenobarbital in 1911, and its powerful anti-epileptic properties were identified in 1912. Phenobarbital remained one of the most widely used epilepsy treatments through the 1970s and is still on the WHO's essential medicines list as of 2014. Suramin, discovered by Bayer scientists in 1916 during World War I, became an anti-parasite drug still sold by Bayer under the brand name Germanin. Bayer kept the formula secret for commercial reasons; it was only decoded and published in 1924 by Ernest Fourneau and his team at the Pasteur Institute.

  • In 1925, Bayer merged with five other German companies, including BASF and Hoechst, to form IG Farben, at the time the world's largest chemical and pharmaceutical company. Bayer's Institute of Pathology and Bacteriology, led by Gerhard Domagk, made a breakthrough discovery in the early 1930s: prontosil, the first commercially available antibacterial drug and the forerunner of all antibiotics. Domagk won the Nobel Prize in Physiology or Medicine in 1939, but the Nazi Party forced him to refuse it, because German citizens had been barred from accepting Nobel prizes after the 1935 Peace Prize went to the pacifist Carl von Ossietzky. Under the Nazi regime, IG Farben used slave labor in factories built inside concentration camps. By 1943, nearly half of IG Farben's 330,000-person workforce consisted of slaves or conscripts, including 30,000 prisoners from Auschwitz alone. Helmuth Vetter, an SS captain and Bayer group employee, conducted medical experiments on inmates at Auschwitz and at the Mauthausen concentration camp. In one documented study of an anaesthetic, the company paid 170 Reichsmarks per person to use 150 female Auschwitz inmates. A Bayer employee wrote to Rudolf Hoss, the Auschwitz commandant, that the women "died during the experiments" and requested another group "to the same number and at the same price." After the war, Fritz ter Meer, who helped plan the Monowitz camp and the Buna Werke factory where 25,000 forced laborers were deployed, was tried at the IG Farben Trial. He was sentenced to seven years but released in 1950 and, despite his conviction as a war criminal, was elected chairman of Bayer AG's supervisory board in 1956, a position he held until 1964. Bayer's CEO Helge Wehmeier offered a public apology to Elie Wiesel in 1995.

  • IG Farben was split into its constituent companies in 1951, and Bayer re-emerged as Farbenfabriken Bayer AG before taking the name Bayer AG in 1972. The company recovered quickly, playing a role in the West German economic revival. Controversy, however, followed close behind. In 1978, Bayer purchased Miles Laboratories, gaining Factor VIII, a clotting agent used to treat hemophilia. By 1983, the CDC had identified contaminated blood products as a source of HIV infection. Bayer and its competitors developed heat-treated replacements, introduced in early 1984. But documents that emerged in 2003 showed that Cutter Laboratories, Bayer's subsidiary, continued to sell unheated blood products in Malaysia, Singapore, Indonesia, Japan, and Argentina until 1985, to offload inventory it could no longer sell in Europe and the United States. Thousands of hemophiliacs who received the tainted product developed AIDS. In 1997, Bayer and three other makers agreed to pay $660 million to settle cases on behalf of more than 6,000 infected hemophiliacs in the United States. In the late 1990s, Bayer also introduced the statin drug Baycol; after 52 deaths were linked to it, the drug was discontinued in 2001. Trasylol, used to control surgical bleeding, was withdrawn worldwide in 2007 after evidence of increased mortality emerged, partly because Bayer scientists had failed to share a relevant ongoing study with the FDA during a 2006 safety review.

  • In May 2016, Bayer offered to buy the American biotechnology company Monsanto for $62 billion. Monsanto rejected the first offer as too low. By September 2016, Monsanto agreed to a revised $66 billion offer, making it the largest acquisition ever undertaken by a German company. Regulatory approval required Bayer to sell significant agricultural assets to BASF. The European Union approved the deal on the 21st of March 2018, and the United States approved it on the 20th of May 2018. The sale closed on the 7th of June 2018, and the Monsanto brand was discontinued. Two months after the deal closed, a U.S. jury ordered Monsanto to pay $289 million to a school groundskeeper who claimed the herbicide Roundup had caused his non-Hodgkin's lymphoma. Bayer's share price fell roughly 14%, erasing about $14 billion in market value on the day of the verdict. That figure was later reduced to $78.5 million on appeal, then further to $21.5 million in June 2020. Roundup litigation multiplied. By 2023, around 165,000 claims had been filed against Roundup, with more than 50,000 still pending. In June 2020 alone, Bayer agreed to pay $9.6 billion to settle more than 10,000 lawsuits, a sum meant to cover 75% of outstanding claims. By 2023, Bayer's market value had declined by more than 60% from its 2016 level, leaving the company worth less than half of what it paid for Monsanto.

  • Crop Science, representing Bayer's agricultural operations, accounted for 48.8% of the company's sales by 2023. Pharmaceuticals contributed 38.0% and Consumer Health 12.7%. Top pharmaceutical products as of 2014 included Xarelto, a blood thinner that Bayer and Johnson and Johnson settled for $775 million in 2019 over claims that patients had not been properly warned about fatal bleeding risks. In May 2026, Bayer announced plans to buy Perfuse Therapeutics for up to $2.45 billion, including a $300 million upfront payment, signaling continued expansion into new therapeutic areas. Among the company's consumer brands are Aspirin, Aleve, Claritin, Coppertone, and Berocca. The Bayer cross logo, introduced in 1904, remains an illuminated landmark in Leverkusen. The company also owns the Bundesliga football club Bayer Leverkusen, tracing back to the sports club TuS 04 it founded in 1904. Bayer's R&D expenditure grew by 22.6% in 2025, the highest rate among any of the company's recent financial reporting periods.

Common questions

When was Bayer AG founded and who founded it?

Bayer AG was founded in 1863 in Barmen, Germany, by dye salesman Friedrich Bayer (1825-1880) and master dyer Johann Friedrich Weskott (1821-1876). It was established as a dyestuffs company before expanding into pharmaceuticals and other fields.

Who invented aspirin and what is Bayer's role in its history?

The underlying compound, acetylsalicylic acid, was first described by French chemist Charles Frederic Gerhardt in 1853. Bayer registered the Aspirin trademark worldwide in 1899. The discovery of the specific formulation is disputed between Bayer chemist Arthur Eichengrün and research assistant Felix Hoffmann, with most historians crediting both.

Did Bayer originally sell heroin?

Yes. Bayer trademarked and marketed heroin (diacetylmorphine) from 1898 to 1910 as a cough suppressant and non-addictive substitute for morphine. The name came from heroisch, the German word for heroic. Bayer did not synthesize heroin first but was the leading force in commercializing it.

What was Bayer's role in the Holocaust and IG Farben?

In 1925 Bayer merged with five other German companies to form IG Farben. By 1943, nearly half of IG Farben's 330,000-person workforce consisted of slave laborers or conscripts, including 30,000 Auschwitz prisoners. A Bayer group employee conducted lethal medical experiments on inmates, and convicted war criminal Fritz ter Meer was later elected chairman of Bayer AG's supervisory board in 1956.

Why is Bayer's acquisition of Monsanto considered one of the worst corporate mergers in history?

Bayer acquired Monsanto for $66 billion in 2018. Roundup herbicide litigation that followed caused massive financial and reputational damage, with Bayer agreeing to pay $9.6 billion in June 2020 to settle more than 10,000 lawsuits. By 2023, Bayer's market value had declined by more than 60% from its 2016 level, leaving the company worth less than half of what it paid for Monsanto.

What happened with Bayer's contaminated blood products and hemophiliacs?

After Bayer's Cutter Laboratories subsidiary identified HIV contamination in its Factor VIII blood products in the mid-1980s, documents that emerged in 2003 showed that Cutter continued selling unheated, contaminated products in Malaysia, Singapore, Indonesia, Japan, and Argentina until 1985. Thousands of hemophiliacs developed AIDS as a result. In 1997, Bayer and three other makers agreed to pay $660 million to settle cases for more than 6,000 infected hemophiliacs in the United States.

All sources

209 references cited across the entry

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  2. 3webIkea and Other Brand Names You've Been MispronouncingSusanna Kim — September 4, 2014
  3. 5bookThe selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023)((World Health Organization)) — World Health Organization — 2023
  4. 10newsLaw No. 9Allied Control Council
  5. 11webBayer
  6. 14newsHow Bayer-Monsanto Became One of the Worst Corporate Deals—in 12 ChartsRuth Bender Graphics by Merrill Sherman — 28 August 2019
  7. 16newsBayer Tries Again to Limit Roundup LiabilitySara Randazzo — 2021-02-03
  8. 22news'Genericide': Brands destroyed by their own successSimon Tulett — 28 May 2014
  9. 23journalAspirin: A Historical and Contemporary Therapeutic OverviewValentin Fuster et al. — 22 February 2011
  10. 24webWHO Model List of EssentialMedicinesWorld Health Organization — October 2013
  11. 25journalThe discovery of aspirin: a reappraisalW. Sneader — 2000-12-23
  12. 27press releaseFelix Hoffmann ist der "Vater" des AspirinBayer AG, courtesy of LaHave Media Services Limited — September 1999
  13. 28press releaseJewish Scientist's Claim to Discover Aspirin Denied by NazisRoyal Society of Chemistry — 1999
  14. 29journalThe discovery of aspirin: a reappraisalSneader, Walter — 23 December 2000
  15. 30journalThe historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potentialJ.G. Mahdi et al. — April 2006
  16. 32webFelix Hoffmann8 December 2017
  17. 34journalThe discovery of heroinWalter Sneader — 21 November 1998
  18. 35journalHow phenobarbital revolutionized epilepsy therapy: the story of phenobarbital therapy in epilepsy in the last 100 yearsYasiry Z, Shorvon SD — December 2012
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  22. 40journalSur une nouvelle série de médicaments trypanocidesE. Fourneau et al. — 1924
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  24. 43webGerhard DomagkScience History Institute — 4 December 2017
  25. 44webI.G. AuschwitzWollheim Memorial, Fritz Bauer Institute
  26. 45webOther doctor-perpetratorsAuschwitz-Birkenau Memorial and Museum
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  28. 47newsIG Farben Opens Factory at AuschwitzDaryl Worthington — 20 May 2015
  29. 48newsStock of former Nazi chemicals giant to be delistedGerhard Schneibel — 19 August 2011
  30. 49webFritz (Friedrich Hermann) ter Meer (1884–1967)Wollheim Memorial, Fritz Bauer Institute
  31. 51webAssessment of historical evidence on Primodos and congenital malformations – a synopsisMedicines and Healthcare products Regulatory Agency — 2014
  32. 53news2 Paths of Bayer Drug in 80's: Riskier One Steered OverseasWalt Bogdanich et al. — 19 September 2003
  33. 54journalWithdrawal of cerivastatin from the world marketC. Furberg et al. — 2001
  34. 57webBayer Annual Report – 2018Bayer — 2018
  35. 59journalHow we choose factor VIII to treat hemophiliaMannucci PM, Mancuso ME, Santagostino E — 2012
  36. 61journalNew oral anticoagulants are not superior to warfarin in secondary prevention of stroke or transient ischemic attacks, but lower the risk of intracranial bleeding: insights from a meta-analysis and indirect treatment comparisonsSardar P, Chatterjee S, Wu WC, Lichstein E, Ghosh J, Aikat S, Mukherjee D — 2013
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  39. 68newsF.D.A. Says Bayer Failed to Reveal Drug Risk StudyGardiner Harris — 30 September 2006
  40. 72webAprotinin Reintroduction Puts Lives at Risk in Canada, EUWood, Shelly — 29 September 2014
  41. 73journalIII. Aprotinin and cardiac surgery: a sorry tale of evidence misusedMcMullan V, Alston RP — 2013
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  45. 98press releaseSale of Roche Consumer Health to Bayer completedRoche — 3 January 2005
  46. 103web2005 a Record Year for Schering AGShering AG press release, PR Newswire — 20 February 2006
  47. 105newsBayer acquires Schering in €17bn dealKatherine Griffiths — 25 June 2006
  48. 108newsAlgeta Board OKs $2.9B Acquisition by Bayer15 January 2014
  49. 116webBayer's Announced Acquisition Adds Needed BoostDamien Conover — 26 October 2020
  50. 123newsBayer defies critics with $62 billion Monsanto offerLudwig Burger et al. — 23 March 2016
  51. 130newsBayer Clears EU Hurdle for Monsanto Deal With BASF SaleAoife White — Bloomberg News — 21 March 2018
  52. 133press releaseBayer closes Monsanto acquisitionBayer AG — 7 June 2018
  53. 138webNames, Facts, Figures about BayerBayer — 31 December 2015
  54. 143newsBayer Settles With Farmers Over Modified Rice SeedsBloomberg L.P. — 1 July 2011
  55. 152inlineBayer
  56. 158bookEssential Concepts in ToxicogenomicsWilliam B. Mattes — 2008
  57. 160webIMI Call Topics 2008Innovative Medicines Initiative — European Commission
  58. 164webBayer to Sell Diabetes Unit to KKR Unit for $1.15 BillionMakiko Kitamura — Bloomberg — 10 June 2015
  59. 165newsBayer to Spin Off Plastics Group to Focus on Health CareChad Bray — 18 September 2014
  60. 178webThe Index
  61. 179webBayer Takes the Hit After Monsanto Loses Roundup Cancer TrialJoel Rosenblatt et al. — 13 August 2018
  62. 181newsRoundup cancer verdict sends Bayer shares slidingLudwig Burger — 13 August 2018
  63. 188newsBayer Loses Roundup Weedkiller AppealSara Randazzo — Dow Jones & Company — 20 July 2020
  64. 190journalGlyphosate toxicity and carcinogenicity: a review of the scientific basis of the European Union assessment and its differences with IARCJose V. Tarazona et al. — 3 April 2017
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  66. 200journalBlood money: Bayer's inventory of HIV-contaminated blood products and third world hemophiliacs.M. Khoshnood et al. — California State University — 2014
  67. 201webBayer's Dicamba Hit Tests Patience of Frustrated InvestorsJef Feeley et al. — February 17, 2020
  68. 209newsBayer's $650 Million PCB Pollution Settlement Rejected by JudgeJoel Rosenblatt et al. — 1 December 2020