Short answers, pulled from the story.
The first confirmed outbreak of the sweating sickness arrived in London on the 19th of September 1485. This event occurred just weeks after Henry VII secured the throne at the Battle of Bosworth. The disease killed several thousand people within days, including two lord mayors, six aldermen, and three sheriffs.
Arthur, Prince of Wales, the eldest son of Henry VII, died of the sweating sickness at Ludlow Castle on the 2nd of April 1502. He was just six months short of his sixteenth birthday when the illness claimed his life. His wife Catherine of Aragon also fell ill but recovered while he succumbed to the disease.
The sweating sickness spread to Hamburg by a ship from England in July 1529 and traveled along the Baltic coast to Denmark, Sweden, and Norway. It reached cities such as Strasbourg, Frankfurt, Cologne, Marburg, and Göttingen by September of that year. The disease emerged simultaneously in Antwerp and Amsterdam on the morning of the 27th of September 1529.
Researchers have noted that symptoms overlap with Hantavirus hemorrhagic fever with renal syndrome and have proposed an unknown hantavirus as the cause. Hantavirus species are zoonotic diseases carried by bats, rodents, and several insectivores. In 2004, microbiologist Edward McSweegan suggested the disease may have been an outbreak of anthrax poisoning from raw wool or infected animal carcasses.
The last major outbreak of the sweating sickness occurred in England in 1551, beginning in Shrewsbury in April. The disease killed around 1,000 people before spreading quickly throughout the rest of England and all but disappearing by October. This final outbreak marked the end of the sweating sickness epidemics that had plagued England and continental Europe for nearly seventy years.