Short answers, pulled from the story.
The year 1623 marked the publication of the First Folio, a collection of William Shakespeare's plays that included an engraving by Martin Droeshout on its title page. This image stands as one of only two representations unambiguously identified with the playwright.
The second definitive image is a half-length bust located in the choir of Holy Trinity Church in Stratford-upon-Avon. This sculpture must have been erected by 1623 when it was referenced in the introduction to the First Folio.
In 2006 the National Portrait Gallery published a report by Tarnya Cooper stating this painting holds the only real claim to being done from life. The portrait attributed to John Taylor dates to about 1610 and bears the name Chandos because it once belonged to the Duke of Chandos.
An Ashbourne portrait identified as Shakespeare in 1847 currently hangs in the Folger Shakespeare Library but was later revealed through X-ray examination to be a retouched portrait of Edward de Vere. Restoration work in 1979 uncovered Hugh Hamersley's coat of arms painted over the original sitter.
Pablo Picasso created numerous variations on Shakespeare's face reduced to minimal form for the four hundredth anniversary of his birth in 1964. Louis Aragon wrote an essay to accompany these drawings.