Short answers, pulled from the story.
The Mughal, Affan Wars began on the 21st of April 1526 with the Battle of Panipat. This battle saw Babur defeat the Delhi Sultanate's Lodi dynasty using gunpowder and field artillery to seize control of Delhi and northern India.
Sher Shah Suri led the Sur Empire which ruled over India from 1540 to 1556. He defeated the Mughal Emperor Humayun in the Battle of Chausa in 1539 and the Battle of Kanauj in 1540 to establish this formidable Afghan state.
The Roshani movement was a deviant Sufism movement preaching Wahdat al-Wujud that grew in Peshawar to resist Mughal influence. It was founded by the charismatic leader Pir Roshan who spent his life in conflict with the Mughals until his death in 1572.
Mughal historian Khafi Khan claims more than 40,000 Mughal soldiers and officers were killed in the defeat at the Karakar and Malandari Pass. Abd al-Qadir Badayuni claims more than 8,000 Mughal soldiers and officers were killed in the same engagement.
The final phase of the Mughal, Afghan Wars ended in 1752 with Ahmad Shah Durrani invading India. Ahmad Shah Durrani and his forces captured Lahore from the Mughals in a series of campaigns that signaled the end of Mughal dominance in the region.