Skip to content

Questions about Deconvolution

Short answers, pulled from the story.

Who developed the foundations of deconvolution and when?

Norbert Wiener of the Massachusetts Institute of Technology laid the foundations for deconvolution and time-series analysis in his 1949 book "Extrapolation, Interpolation, and Smoothing of Stationary Time Series". The work was based on research Wiener had conducted during World War II that had been classified at the time.

What is deconvolution used for in seismology?

In reflection seismology, deconvolution is used to strip a seismic wavelet from a recorded seismogram and recover the Earth-reflectivity function, which reveals the geological structure underground. Enders Robinson and colleagues including Wiener, Norman Levinson, and Paul Samuelson developed the convolutional model for this purpose starting in 1950 at MIT.

How was deconvolution used to fix Hubble Space Telescope images?

Early Hubble Space Telescope images were distorted by a flawed mirror and were sharpened using deconvolution before physical corrections were made. The technique works by determining the point spread function that describes the distortion, then convolving the acquired image with its inverse to recover the original, undistorted image.

What is blind deconvolution and where is it applied?

Blind deconvolution is a technique used when the distortion function is unknown; it works by systematically testing different possible point spread functions and assessing whether the image improves. It is well established in astronomy and is also used in fluorescence microscopy and fluorescence spectral imaging. The Richardson-Lucy algorithm is the most common iterative method for blind deconvolution.

What are the main biological applications of deconvolution?

Deconvolution is applied in tracer kinetics to estimate hormone secretion rates from blood concentration measurements. It is also used to recover blood glucose concentration from interstitial glucose readings, which are a time- and amplitude-distorted version of the actual blood glucose level.

Why does noise make deconvolution difficult?

When a noisy signal is treated as noiseless, the statistical estimate of the distortion function g is incorrect, which in turn produces an incorrect estimate of the original signal. The lower the signal-to-noise ratio, the worse the result. Techniques such as Wiener deconvolution improve the estimate by incorporating knowledge about the character of the noise, for example whether it behaves as white noise.