Short answers, pulled from the story.
The Apple Boutique opened on the 7th of December 1967 and closed on the 31st of July 1968, operating for less than eight months. It was located at the corner of Baker Street and Paddington Street in Marylebone, London.
The mural was designed by the Fool, a design collective formed by Dutch artists Simon Posthuma and Marijke Koger along with Josje Leeger, Barry Finch, and Simon Hayes. Art students employed by Barry Finch painted it across the building's facades between the 10th and the 12th of November 1967. Westminster City Council ordered it painted over because planning consent had never been granted.
The Apple Boutique closed because it was a financial disaster, with losses eventually reaching £200,000. Theft was widespread among both customers and staff, and the Beatles decided to refocus Apple Corps on records, films, and electronics. Paul McCartney stated in the closing press release that the shops had simply become like every other boutique in London.
The Beatles gave all remaining stock away for free on the 31st of July 1968, allowing one item per person. Hundreds of people arrived after an announcement was placed in the newspaper, and the shop emptied within hours. The crowd nearly rioted and police attended to manage the scene.
The Beatles gave the Fool collective £100,000 to design and stock the shop in September 1967. By the time it closed, total losses had reached approximately £200,000. The biggest single loss at the end was the deliberate giveaway of all remaining stock.
The original Georgian townhouse dating from 1795 was demolished sometime between October 1969 and January 1972. It was replaced by Travelscene House, an office building taller than the original, with neo-Georgian facades described as incorrectly proportioned. A blue plaque noting both John Lennon's and George Harrison's involvement was installed at the site on the 17th of March 2013.