French fur traders Pierre Laclède and Auguste Chouteau established the settlement on the 14th of February 1764.
The city had 301,578 residents remaining as of the 2020 Census after losing 64.8% of its population since 1950.
The Gateway Arch completed the 28th of October 1965 stands at 630 feet making it the world's tallest arch and tallest human-made monument in the Western Hemisphere.
Suburbanization from the 1950s through the 1990s dramatically reduced the city's population alongside industrial restructuring and job losses.
Forest Park occupies 1,400 acres on the western edge of the city and houses five major institutions including the St. Louis Art Museum and the Missouri History Museum.