Short answers, pulled from the story.
Margaret of Austria, Duchess of Savoy was born on the 10th of January 1480 in Brussels. Her birth occurred during a period of political instability as her mother Mary of Burgundy died when Margaret was only two years old.
Margaret of Austria, Duchess of Savoy served as the Governor of the Habsburg Netherlands from 1507 to 1515 and again from 1519 until her death. She acted as the de facto queen of the region while her brother Philip died and her nephew Charles V was too young to rule.
Margaret of Austria, Duchess of Savoy died on the 30th of November 1530 after stepping on broken glass on the 15th of November 1530. The injury led to gangrene and the amputation of her leg, and she passed away between midnight and one o'clock after being given a strong dose of opium.
Margaret of Austria, Duchess of Savoy maintained a library of over 380 books and employed artists like Jan van Eyck and Josquin des Prez. Her court in Mechelen became a proto-museum featuring exotic natural objects and treasures from Hernán Cortés.
Margaret of Austria, Duchess of Savoy kept the embalmed heart of her second husband Philibert II, Duke of Savoy as a gesture of devotion after his death in 1504. This act earned her the title Dame de deuil or Lady of Mourning and demonstrated her profound grief.