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Questions about Lymphoma

Short answers, pulled from the story.

When was lymphoma first described by Thomas Hodgkin?

Thomas Hodgkin published the first description of lymphoma in 1832. This publication specifically detailed the form that now bears his name.

What are the common signs and symptoms of lymphoma?

Signs and symptoms include enlarged painless lymph nodes, fever, drenching sweats at night, unintended weight loss, itching, and constant fatigue. The sweats associated with this condition occur most frequently during nighttime hours.

How is lymphoma definitively diagnosed through medical testing?

Lymphoma is definitively diagnosed by a lymph-node biopsy involving partial or total excision examined under a microscope. Additional tests may include immunophenotyping, flow cytometry, fluorescence in situ hybridization, and medical imaging to determine spread to organs like the lungs, liver, and brain.

Which cell type marks Hodgkin lymphoma according to WHO classification?

A Hodgkin lymphoma is marked by the presence of a specific cell called the Reed Sternberg cell. The World Health Organization classification groups lymphomas by cell type and defining phenotypic, molecular, or cytogenetic characteristics.

What percentage of all cancers do lymphomas represent worldwide in 2012?

Worldwide, lymphomas developed in 566,000 people in 2012 and caused 305,000 deaths. They make up 3.4% of all cancers, making them as a group the seventh-most-common form globally.

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