Short answers, pulled from the story.
Guile is a fictional character from Capcom's Street Fighter series, introduced in 1991's Street Fighter II as one of the eight original World Warriors. He is a United States Air Force pilot who starts the series as a major and is promoted to colonel by Street Fighter V. He is driven by the death of his friend Charlie at the hands of M. Bison.
Guile's two signature moves are the Sonic Boom and the Flash Kick. Both are performed by holding a direction on the joystick and then pushing the opposite way with a punch or kick.
Jean-Claude Van Damme played Guile, credited as William F. Guile, in the 1994 live-action Street Fighter film. In that film he commands A.N. forces while searching for General M. Bison.
Guile's design and hairstyle are based on Rudol von Stroheim and Jean-Pierre Polnareff, two characters from the manga JoJo's Bizarre Adventure. His name also references a JoJo's Bizarre Adventure character who was named after The J. Geils Band.
Charlie Nash is Guile's best friend and co-pilot, and he dies when Shadaloo's base explodes in Street Fighter Alpha 3. He is later resurrected by an unknown assailant and reappears in Street Fighter V, where he sacrifices himself again to weaken M. Bison.
WWE superstar Cody Rhodes is set to play Guile in an upcoming live-action adaptation directed by Kitao Sakurai.