Short answers, pulled from the story.
Capcom developed Guile as a pilot from the United States Air Force to appeal specifically to American fans. Noritaka Funamizu, Capcom Research and Design head, stated that western audiences considered him the game's main character.
Players control Guile using two signature moves called Sonic Boom and Flash Kick which require holding directions on the joystick. The Sonic Boom requires pushing left or right followed by a punch while the Flash Kick demands holding down and then releasing upward while kicking.
Fortnite Battle Royale introduced his skin on the 3rd of August 2021 according to the provided text. Exoprimal will feature a playable Guile skin soon following this release date.
Jean-Claude Van Damme played William F. Guile in the 1994 live-action film that used digitized footage for its 1995 arcade and home versions. Van Damme posed for animation frames in those games but declined to reprise the role in Street Fighter: The Legend of Chun-Li.
Masane Tsukayama voiced Guile in the Japanese original of Street Fighter II: The Animated Movie while Kirk Thornton provided the English dub under the name Donald Lee. Tessho Genda voiced him in Street Fighter II V where he acts as Master Sergeant.