Common questions about Cannabis (drug)

Short answers, pulled from the story.

When and where was the earliest evidence of cannabis smoking discovered?

Archaeologists discovered the earliest known evidence of cannabis smoking in the 2,500-year-old tombs of the Jirzankal Cemetery in the Pamir Mountains around 500 BCE. This finding in Western China confirms that ancient Indo-Iranian tribes, including the Scythians, used the plant to induce trance states during funeral ceremonies.

What is the primary psychoactive compound in cannabis and how does it form?

Tetrahydrocannabinol, or THC, is the main psychoactive component of the cannabis plant. When raw cannabis is heated, tetrahydrocannabinolic acid decarboxylates into THC, transforming the non-psychoactive plant material into a potent drug.

What are the health risks associated with cannabis use according to a 2025 study?

A 2025 study found that cannabis users face a nearly threefold increase in mortality rates and a tenfold higher risk of dying by suicide. The drug is also associated with a 29% higher risk of heart attack and a 20% higher risk of stroke.

Which countries have legalized recreational cannabis and when did they do so?

Uruguay became the first country to legalize recreational cannabis in December 2013, followed by Canada in 2018. Germany legalized recreational use in April 2024, and Malta became the first European Union member to legalize cannabis for recreational purposes in 2021.

How has the legal status of cannabis changed in the United States as of 2025?

The United States Department of Justice announced in April 2024 its intention to reclassify cannabis from a Schedule I to a Schedule III controlled substance. This move was signed into executive order on the 18th of December 2025.

What medical conditions can medical cannabis treat according to current evidence?

Medical cannabis is used to treat chemotherapy-induced nausea and vomiting, neuropathic pain, and multiple sclerosis. The drug has also been used to reduce nausea and vomiting during chemotherapy, improve appetite in people with HIV/AIDS, and treat chronic pain and muscle spasms.